I hate having to have a CD in drive, because it's annoying and damages the CD.
It's annoying because I have to change disks every time I want to play a different game.
It damages my disks because they have to be in drive and they have to be put in/out of cd-case. When I do a full installation of game, I should be able to protect my CDs from damage by keeping them in cd-case/safe/cd-album, etc.